The former and current Publishers and Editor are jointly issuing an Expression of Concern on the article entitled

“Lentiviral Vector-Mediated SHC3 Silencing Exacerbates Oxidative Stress Injury in Nigral Dopamine Neurons by Regulating the PI3K-AKT-FoxO Signaling Pathway in Rats with Parkinson's Disease”
[Cell Physiol Biochem 2018;49:971–984; DOI: 10.1159/000493228]
by Jian Gong, Lei Zhang, Qian Zhang, Xiang Li, Xiang-Jun Xia, Yin-Yuan Liu and Qin-Shang Yang.

After the publication of this article, concerns were raised about the integrity of some of the data presented in the article. The authors were unresponsive to our correspondence within the given timeframe. The matter was raised to the research management officers at the corresponding author's institution to request an investigation. Until the conclusion of their investigation, readers should interpret the data presented in the article with caution. Appropriate editorial action will be taken once the investigation is concluded.